Episode 11:
Owner of a Lonely Heart

Air Date: 12/04/2005

Cristina Yang has little sympathy for Constance Ferguson (special guest star Rosanna Arquette), a prison inmate who jeopardizes her health just to get out of solitary confinement. Meanwhile the interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges, Izzie's anger at Alex reaches boiling point, and Dr. Addison Shepherd decides to teach Izzie a very painful lesson.

- description by ABC.com

Grey's Anatomy Music

Artist: Jim Noir
Song: "I Me You"

Artist: Gemma Hayes
Song: "Two Step"

Artist: James Blunt
Song: "Tears & Rain"

Artist: Emiliana Torrini
Song: "Sunny Road"

Artist: Moonbabies
Song: "War On Sound"

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Guest Appearances

Curtis Armstrong .... Robert Martin
Rosanna Arquette .... Constance Ferguson
Patricia Bethune .... Nurse Ginger
Brooke Blanchard .... Jill the Paramedic
Timothy Bottoms .... Carl Murphy
Amie Donegan .... NICU Nurse #2
Monica Garcia .... Peds Nurse
Pat Healy .... Tom Russell
Elaine Kao .... NICU Nurse
Sarah Utterback .... Nurse Olivia
Margaret Welsh .... Dorie Russell